Investigators said the accident happened on KY 192, approximately 10-miles west of London around 1:00 p.m.
Investigators said apparently a Nissan Sentra was westbound on KY 192, when it crossed the centerline and collided with an eastbound Dodge pickup truck head-on.
Investigators said the driver of the Nissan, Bonnie Hancock, 67, of London, was killed.
The driver of the pickup, Lattie Neely, 53, of London, was airlifted to UK Hospital in Lexington, according to the Sheriff’s Office.
The accident remains under investigation.