The Lexington Humane Society said the animals were living in deplorable conditions in a home with no air conditioning.
The Lexington Humane Society said the dogs were surrounded by mounds of feces and carcasses of dead dogs; with limited human interaction, food and water; and abandoned by their owner.
"While offering assistance for these 22 additional animals will put a drain on our staff and financial resources, it is the right thing to do. These animals have lived a terrible life and they deserve a second chance at a life filled with love, which is what we do best here at the Lexington Humane Society," said Susan Malcomb, LHS President.
The Lexington Humane Society is going to evaluate the rescued dogs to determine their medical needs and set a course for treatment.
Once the rescued dogs are deemed healthy, they will be put up for adoption.
The Lexington Humane Society rescued 900-animals from crisis situations outside of Fayette County this past year.