WebMD Medical News
Louise Chang, MD
Oct. 16, 2007 -- Doctors have found a bacterial strain that causes ear
infections and resists all FDA-approved antibiotics for kids.
The bacterial strain also isn't targeted by the pneumococcal conjugate
vaccine PCV7 routinely given to children.
Altering the PCV7 vaccine to cover the drug-resistant bacterial strain might
be a solution. Tests of such a vaccine are under way, note Michael Pichichero,
MD, and Janet Casey, MD.
They work at the University of Rochester and Legacy Pediatrics in Rochester,
Pichichero and Casey spotted the drug-resistant strain of Streptococcuspneumoniae bacteria in nine out of about 1,800 Rochester children who
had a middle ear infection from 2003 to 2006.
The bacterial strain resisted all antibiotics that are approved by the FDA
for use in children.
The doctors describe using "aggressive therapy (either surgery or
levofloxacin also known as Levaquin, an antibiotic unapproved for children)” to
treat the drug-resistant ear infections.
But they warn that it could be "disastrous" for doctors to start using
levofloxacin in kids with difficult-to-treat ear infections, because doing so
could teach the bacteria to resist levofloxacin.
It's not clear how common the drug-resistant ear infection bacteria are
beyond the Rochester patients seen by Pichichero and Casey.
The report appears in tomorrow's edition of The Journal of the American
(How many ear infections has your baby had this year? How do you treat
them? Talk with other parents on WebMD's Parenting: 9 - 12 Months board.)
SOURCES: Pichichero, M. The Journal of the American Medical
Association, Oct. 17, 2007; vol 298: pp 1772-1778. Bancroft, E. The
Journal of the American Medical Association, Oct. 17, 2007; vol 298: pp
1803-1804. News release, JAMA/Archives.
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