Future Hall of Fame cornerback Champ Bailey is unemployed again after the New Orleans Saints released him on Saturday en route to getting to the NFL's 53-man roster limit.
The Pittsburgh Steelers announced on Wednesday that "Mean Joe" Greene's No. 75 has been retired by the franchise.
Carolina Panthers quarterback Cam Newton missed practice on Wednesday with sore ribs but his coach remains optimistic he'll be OK to start the season Sunday against Tampa Bay.
While the Titans cut ties with the long-time running back Chris Johnson in the offseason, allowing him to sign with the New York Jets, the club brought in a head coach with Super Bowl experience -- something Johnson didn't have.
The San Francisco 49ers activated linebacker NaVorro Bowman from the reserve/physically unable to perform list on Tuesday.
The San Francisco 49ers removed guard Alex Boone from the exempt list in time for the recent holdout to play in Sunday's season opener at Dallas.
The San Francisco 49ers have signed veteran offensive lineman Erik Pears to a two-year contract, the team announced Tuesday.
The San Francisco 49ers have signed running back Alfonso Smith to a one-year contract.
San Francisco 49ers head coach Jim Tomsula formally announced the team's coaching staff on Monday.
The San Francisco 49ers have signed special-teams ace Bubba Ventrone to a one-year contract.
San Francisco 49ers center Daniel Kilgore will undergo surgery Tuesday for a fractured left leg and will be placed on injured reserve.
The San Francisco 49ers have placed disappointing wide receiver Jon Baldwin on waivers, the team announced Sunday.
The San Francisco 49ers waived offensive tackle Jonathan Martin on Thursday.
The San Francisco 49ers released Ray McDonald on Wednesday after police announced that the veteran defensive tackle is the suspect in a sexual assault investigation.
Hall of Famer Bob St. Clair, a 6-foot-9 offensive tackle who played all 11 of his NFL seasons for the San Francisco 49ers, died Monday at the age of 84.
The San Francisco 49ers signed defensive lineman Arik Armstead, their first-round selection in the 2015 draft, to a four-year contract on Friday.
The San Francisco 49ers have signed tight end Derek Carrier to a two-year contract extension through the 2017 season.
San Francisco 49ers linebacker Chris Borland says he's retiring at the age of 24 over concerns about brain trauma.
San Francisco 49ers linebacker Aldon Smith was sentenced to 11 days in jail and three years' probation on weapons and DUI charges but can serve his jail term on a work crew.
San Francisco 49ers linebacker Aldon Smith was suspended nine games without pay on Friday for violating the NFL's Policy and Program for Substance of Abuse and the league's Personal Conduct Policy.
San Francisco 49ers linebacker Patrick Willis will miss Sunday's game against New Orleans.
The San Francisco 49ers officially signed running back Reggie Bush on Wednesday.
Tom Gamble has returned to the San Francisco 49ers as a senior personnel executive.
The San Francisco 49ers will stay in- house for Jim Harbaugh's successor.
The San Francisco 49ers placed linebacker NaVorro Bowman on the physically unable to perform list on Wednesday.
The San Francisco 49ers placed cornerback Chris Cook and center Daniel Kilgore on injured reserve Saturday.
The San Francisco 49ers placed linebacker NaVorro Bowman and nose tackle Glenn Dorsey on season-ending injured reserve.
All-Pro linebacker NaVorro Bowman was officially placed on the reserve/physically unable to perform list by the San Francisco 49ers as the team pared down its active roster to 75 players on Monday.
San Francisco 49ers running back Kendall Hunter suffered a torn ACL during Friday's practice.
San Francisco 49ers running back Marcus Lattimore says he is retiring from football without ever playing a down in the NFL because of the same knee injury that cut short his college career two years ago.
The San Francisco 49ers have re-signed linebacker Desmond Bishop to a one-year contract.
Santa Clara, CA (Sports Network) - The San Francisco 49ers waived running back LaMichael James on Monday.
The San Francisco 49ers released wide receiver Stevie Johnson on Thursday.
The San Francisco 49ers have signed Pro Bowl left tackle Joe Staley to a two-year contract extension through the 2019 season.
The San Francisco 49ers signed nine undrafted free agents on Tuesday, including former South Carolina quarterback Dylan Thompson.
The San Francisco 49ers have signed running back Kendall Hunter to a one-year contract extension.
The San Francisco 49ers signed Australian rugby star Jarryd Hayne to a three-year contact on Tuesday.
While the San Francisco 49ers continue to deal with a slew of offseason defections, the team made a significant addition on Wednesday's second day of free agency.
San Francisco 49ers tight end Vernon Davis is inactive for Sunday's game against the Kansas City Chiefs.
San Francisco 49ers tight end Vernon Davis is out for Sunday's game against the Arizona Cardinals.
San Francisco 49ers tight end Vernon Davis is questionable for Sunday's game against the Kansas City Chiefs.
The San Francisco 49ers will have All- Pro linebacker Aldon Smith on the field for the first time this season on Sunday.
San Francisco 49ers wide receiver Michael Crabtree is listed as questionable for Sunday's season opener against the Dallas Cowboys.
San Francisco 49ers tight end Vernon Davis put in a third straight limited practice on Friday, though the team has termed him questionable to play in this weekend's game against the Philadelphia Eagles.
San Francisco 49ers defensive lineman Glenn Dorsey has signed a two-year contract extension through the 2016 season.
The San Francisco 49ers announced Monday that defensive lineman Justin Smith has decided to retire after 14 NFL seasons.
San Francisco 49ers defensive end Ray McDonald was arrested early Sunday morning on felony charges of domestic violence.
San Francisco 49ers defensive end Ray McDonald will not face charges of domestic violence stemming from an August arrest.
San Francisco 49ers special teams veteran Kassim Osgood will miss the remainder of the season because of a broken hand.