Severe Thunderstorm Warning expires at 4:15 PM on 9/2, issued at 3:37 PM Allen, KY | Auxier, KY | Banner, KY | Beaver, KY

Two New Promising Treatments for MS

Reported by: Lauren Gawthrop
Set Text Size SmallSet Text Size MediumSet Text Size LargeSet Text Size X-Large
Updated: 4/30/2012 7:36 am
Two new Multiple Sclerosis drugs may offer patients more convenient ways to manage the debilitating disease. MS is often treated with injections, but two new studies look at a yearly IV infusion and an oral pill. One of the drugs on the horizon is a yearly IV infusion called Alemtuzumab. 

This drug was studied in over 800 patients with relapsing MS, and results show that it is more effective in treating this type of MS than standard 3-times per week injections of interferon Beta-1A.

In fact, 65% of patients treated with the new drug were relapse-free after two years and some even improved.

Researchers say the drug is convenient and highly effective which makes it attractive, but it's not for everyone. 

"Most likely this drug will be used in patients with very active MS, probably in patients that have tried other medications and either got little benefit or intolerable side effects," said Cleveland Clinic's Dr. Jeffrey Cohen, an MS expert. "Because it's so potent, I think it's unlikely that it will be used as a first treatment for most people."

Additional research looks at a pill called BG-12. It's the second oral medication to treat MS. Researchers studied over 1,400 patients worldwide with relapsing-remitting MS.

BG-12 was compared to placebo and a standard injection called GA. Results show BG-12 reduced annual relapse rates and the number of brain lesions.

Side effects were generally milder than other available MS therapies and include skin flushing, stomach cramps, diarrhea and vomiting mostly during the first few weeks of treatment.

Dr. Robert Fox led the study and believes BG-12 may be an attractive potential therapy for MS.

"Many patients, as you might imagine, prefer an oral pill over an injection and with this therapy being as effective and very well tolerated and very safe, it makes BG-12 a very attractive option for MS patients should it get approved," said Dr. Robert Fox, another MS expert at Cleveland Clinic.

Both studies were presented at the Annual American Academy of Neurology meeting in New Orleans.
0 Comment(s)
Comments: Show | Hide

Here are the most recent story comments.View All

No comments yet!
Most Popular
More than 30 teens escape from detention center
A spokesman says more than 30 teens escaped from a Nashville, Tenn. youth detention center and 17 are still being sought.
Coroner: Elderly Mercer Co. Couple Die in Apparent Murder-Suicide
The Mercer County Coroner has confirmed that an elderly couple were found dead in their home Sunday night following an apparent murder-suicide.
Former High School Football Coach Charged with Sodomy, Sexual Abuse
According to deputies in Pulaski County, a former high school football coach has been arrested on charges of sodomy and sexual abuse.
Police: Shots Fired Near Lexington School
Lexington Police said shots were fired Monday afternoon near Lafayette High School. Although school had been out for the Labor Day holiday, youth football tournament was being held at Lafayette. Video Video
Lexington PD: Argument Between Neighbors Results in Gunfire
An argument between neighbors escalated to at least one shot being fired Monday afternoon, according to Lexington Police. Video Video
Flu RSS Aggregator Widget. Flash Player 9 is required.
Flu RSS Aggregator Widget.
Flash Player 9 is required.

Five Minutes Or Less For Health Widget. Flash Player 9 is required.
Five Minutes Or Less For Health Widget.
Flash Player 9 is required.

Inergize Digital This site is hosted and managed by Inergize Digital. supports children's privacy rights. All persons under the age of 13 MUST have parental permission to use this website and direct parental supervision is strongly recommended.