The lane restrictions will allow crews to perform a detailed inspection of the bridge structure.
Engineers will be using a Snooper Truck to access the deck substructure on the bridge.
Wednesday, northbound traffic will be reduced at mile point 30.6 in Laurel County 9 a.m. - noon, while southbound traffic will be reduced from 12:30-3:30 p.m.
Motorists are advised to use caution during this period and be aware of signage, road crews and other drivers.
The work is dependent on weather conditions.
The date, time, and duration of work may be adjusted if inclement weather or other unforeseen delays occur.
Dial 511 or log on to 511.ky.gov for the latest in traffic and travel information in the Commonwealth of Kentucky.
You can also get traffic information for the District 11 counties at www.facebook.com/KYTCDistrict11.