State Police have reported a tanker truck possibly carrying propane has crashed on I-64 at mile marker 115.
They said the truck was heading east when it crashed, blocking both lanes.
Police, fire crews, EMS, and Haz-mat crews are currently on the scene.
There are no reports of any leaks coming from the truck.
A detour has been set up at the 113 mile marker to route traffic to Highway 60 around the accident.
Traffic is routed back onto the Interstate at mile marker 121.