The Science Hill Police Department on Thursday issued a Golden Alert for James Alfred Woods, 70, of Science Hill.
Police said he suffers from Alzheimer's.
Police said he was last seen carrying a suitcase on Highway 80 in Science Hill.
Police said Woods reportedly told some people he was going to Florida to see his ex-wife.
Woods is 5'4" with grey hair, brown eyes with a scar above his left eye.
Police said he was last seen wearing a black western-style hat, jeans and a white and blue button-up shirt.
If you have any information about Woods' whereabouts, call the Science Hill Police Department at 606-423-3672.