Lexington Police issued a Golden Alert for Dennis Vanderpool.
Police said the Lexington man, who suffers from Alzheimer's disease, went missing around 2:30 p.m. Thursday.
Police said Vanderpool was believed to be traveling in a black, 2001 Ford Ranger pickup with license plate 595 FMP.
Police said he may have been headed to Richmond, Kentucky.
Police said Vanderpool was last seen wearing blue jeans, a green t-shirt and a camouflage print jacket.
Anyone with information should call 9-1-1 immediately.