The Franklin County Sheriff's office said a tip helped deputies seize money, guns and drugs.
Investigators said they made the bust after obtaining a search warrant for an apartment on East Main Street in Frankfort.
Deputies said it was part of an investigation into illegal drug sales.
The Sheriff's Office said it found morphine, oxycodone, hydrocodone, marijuana, four loaded handguns and cash.
According to deputies, Joel Hurst and Gabriel Gordon, Frankfort, face charges in the case.
Investigators also arrested Henry Tolliver of Lancaster, California.