The Franklin County Sheriff's Office said deputies found large amounts of prescription drugs, cash and guns Thursday inside a house.
Investigators said the evidence was seized when a drug-related search warrant was executed on the 100 block of Rock Creek.
Deputies said drugs were being sold at the home.
Investigators said they also recovered five pistols and several-thousand dollars in cash from the residence.
Deputies arrested Charles W. Cook, 68, and Tammy Dent, 54, on charges including drug trafficking.